Telomeric transcription and telomere rearrangements in quiescent cells.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2020.01.034
Abstract: Despite the condensed nature of terminal sequences, the telomeres are transcribed into a group of non-coding RNAs, including the TElomeric Repeat-containing RNA (TERRA). Since the discovery of TERRA, its evolutionary conserved function has been confirmed,… read more here.
Keywords: transcription; transcription telomere; quiescent cells; rearrangements quiescent ... See more keywords
Staging quiescent cells
Sign Up to like & getrecommendations! Published in 2018 at "Science"
DOI: 10.1126/science.360.6384.44-p
Abstract: Stem Cells Tissue-specific stem cells either divide or wait in a quiescent state until needed by the body. Quiescent stem cells have been thought to reside in the G stage before activating to reenter the… read more here.
Keywords: staging quiescent; stem; stem cells; quiescent cells ... See more keywords
Battling quiescence for tumor eradication: too good to be true?
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DOI: 10.18632/oncotarget.26452
Abstract: Efforts to differentiate mechanisms underlying tumor quiescence and proliferation have occurred mostly in leukemia [1], and in hormone-driven cancers of the breast [2] or the prostate [3, 4]. In our previous study, we isolated quiescent… read more here.
Keywords: quiescent cells; pkh; quiescence; trim44 ... See more keywords
Diverse geroprotectors differently affect a mechanism linking cellular aging to cellular quiescence in budding yeast
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DOI: 10.18632/oncotarget.28256
Abstract: We propose a hypothesis of a mechanism linking cellular aging to cellular quiescence in chronologically aging budding yeast. Our hypothesis posits that this mechanism integrates four different processes, all of which are initiated after yeast… read more here.
Keywords: quiescent cells; quiescence; aging cellular; mechanism ... See more keywords
Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells
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DOI: 10.7150/thno.63763
Abstract: Rationale: Recurrent and metastatic cancers often undergo a period of dormancy, which is closely associated with cellular quiescence, a state whereby cells exit the cell cycle and are reversibly arrested in G0 phase. Curative cancer… read more here.
Keywords: quiescent cells; quiescent cancer; cancer cells; cancer ... See more keywords