Central levels of tryptophan metabolites in subjects with bipolar disorder
Sign Up to like & getrecommendations! Published in 2021 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2020.11.018
Abstract: The kynurenine pathway of tryptophan degradation produces several neuroactive metabolites such as kynurenic acid (KYNA), quinolinic acid (QUIN), and picolinic acid (PIC) thought to be involved in the pathophysiology of psychosis, major depression, and suicidal… read more here.
Keywords: suicidal behavior; quin; kynurenine pathway; bipolar disorder ... See more keywords
Sustained Activation of JNK Induced by Quinolinic Acid Alters the BDNF/TrkB Axis in the Rat Striatum
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.04.034
Abstract: Oxidative stress secondary to excitotoxicity is a common factor in the physiopathology of a variety of neurological disorders. In response to oxidative stress, several signaling pathways, such as MAPK, are activated or inactivated. Mitogen-activated protein… read more here.
Keywords: jnk; quin; bdnf trkb; induced quinolinic ... See more keywords
Dicarbonyl cis-[M(CO)2(N,O)(C)(P)] (M = Re, 99mTc) Complexes with a New [2 + 1 + 1] Donor Atom Combination.
Sign Up to like & getrecommendations! Published in 2018 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.8b01014
Abstract: The synthesis and characterization of the dicarbonyl mixed ligand cis-[Re(CO)2(quin)(cisc)(PPh3)] complex, 4, where quin is the deprotonated quinaldic acid, cisc is cyclohexyl isocyanide, and PPh3 is triphenylphosphine, is presented. The synthesis of 4 proceeds in… read more here.
Keywords: dicarbonyl; atom combination; new donor; quin ... See more keywords
Cleaner and stronger: how 8-quinolinolate facilitates formation of Co(III)-thiolate from Co(II)-disulfide complexes.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt02106d
Abstract: The formation of Co(III)-thiolate complexes from Co(II)-disulfide complexes using the anionic ligand 8-quinolinolate (quin-) has been studied experimentally and quantum chemically. Two Co(II)-disulfide complexes [Co2(LxSSLx)(Cl)4] (x = 1 or 2; L1SSL1 = 2,2'-disulfanediylbis(N,N-bis(pyridin-2-ylmethyl)ethan-1-amine; L2SSL2 =… read more here.
Keywords: disulfide complexes; thiolate; quin; iii thiolate ... See more keywords
Peripheral interleukin-6-associated microglial QUIN elevation in basolateral amygdala contributed to cognitive dysfunction in a mouse model of postoperative delirium
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.998397
Abstract: Background Developing effective approaches for postoperative delirium has been hampered due to the lack of a pathophysiologically similar animal model to offer insights into the pathogenesis. The study, therefore, aimed to develop a delirium-like mouse… read more here.
Keywords: quin; delirium; postoperative delirium; model ... See more keywords