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   Articles with "quinazoline derivative" as a keyword



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Exploring deep insights into the interaction mechanism of a quinazoline derivative with mild steel in HCl: electrochemical, DFT, and molecular dynamic simulation studies

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recommendations! Published in 2019 at "Journal of Adhesion Science and Technology"

DOI: 10.1080/01694243.2018.1554764

Abstract: Abstract A novel quinazoline derivative, 3-cyclopropyl-3,4-dihydroquinoline-2(1H)-One (CPHQ), was successfully designed and synthesized. Then, its corrosion inhibition behavior on carbon steel (CS) surface in 1.0 M HCl at different temperatures was investigated using chemical, electrochemical and theoretical… read more here.

Keywords: dft; steel; cphq; quinazoline derivative ... See more keywords

A Natural Quinazoline Derivative from Marine Sponge Hyrtios erectus Induces Apoptosis of Breast Cancer Cells via ROS Production and Intrinsic or Extrinsic Apoptosis Pathways

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recommendations! Published in 2019 at "Marine Drugs"

DOI: 10.3390/md17120658

Abstract: Here, we report the therapeutic potential of a natural quinazoline derivative (2-chloro-6-phenyl-8H-quinazolino[4,3-b]quinazolin-8-one) isolated from marine sponge Hyrtios erectus against human breast cancer. The cytotoxicity of the compound was investigated on a human breast carcinoma cell… read more here.

Keywords: natural quinazoline; apoptosis; quinazoline derivative; sponge hyrtios ... See more keywords
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Disruption of IGF-1R signaling by a novel quinazoline derivative, HMJ-30, inhibits invasiveness and reverses epithelial-mesenchymal transition in osteosarcoma U-2 OS cells

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recommendations! Published in 2018 at "International Journal of Oncology"

DOI: 10.3892/ijo.2018.4325

Abstract: Osteosarcoma is the most common primary malignancy of the bone and is characterized by local invasion and distant metastasis. Over the past 20 years, long-term outcomes have reached a plateau even with aggressive therapy. Overexpression… read more here.

Keywords: igf signaling; quinazoline derivative; igf; epithelial mesenchymal ... See more keywords