Wang-OSO3H catalyzed green synthesis of bioactive isoindolo[2,1-a]quinazoline-5,11-dione derivatives: An unexpected observation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131922
Abstract: ABSTRACT The sulphonic acid-functionalized Wang resin (Wang-OSO3H) was explored as a polymeric and recoverable acidic catalyst for the synthesis of isoindolo[2,1-a]quinazoline-5,11-dione derivatives under green conditions. Thus the Wang-OSO3H catalyzed MCR of isatoic anhydride, 2-formylbenzoic acid… read more here.
Keywords: oso3h catalyzed; wang oso3h; isoindolo quinazoline; quinazoline dione ... See more keywords
Activation and Utilization of CO2 Using Ionic Liquid or Amine-Functionalized Basic Nanocrystalline Zeolites for the Synthesis of Cyclic Carbonates and Quinazoline-2,4(1H,3H)-dione
Sign Up to like & getrecommendations! Published in 2017 at "Industrial & Engineering Chemistry Research"
DOI: 10.1021/acs.iecr.7b01406
Abstract: CO2 was activated and used as a reactant for the preparation of cyclic carbonates and quinazoline-2,4(1H,3H)-dione using functionalized basic nanocrystalline zeolite Nano-ZSM-5 as catalysts. Nano-ZSM-5 was treated with aqueous NH3 solution to prepare basic Nano-ZSM-5.… read more here.
Keywords: carbonates quinazoline; quinazoline dione; co2; nano zsm ... See more keywords
Ultrafast photoresponse organic phototransistors based on pyrimido[4,5-g]quinazoline-4,9-dione polymer
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Materials Chemistry C"
DOI: 10.1039/c7tc03023a
Abstract: We report the photoresponse characteristics of a pyrimido[4,5-g]quinazoline-4,9-dione (PQ) based polymer, PPQ2T-BT-24, which served as an active channel layer in organic phototransistors (OPTs). OPTs using this polymer showed very short rise time of 3 ms… read more here.
Keywords: organic phototransistors; photoresponse; polymer; quinazoline dione ... See more keywords
Design and biological evaluation of 3-substituted quinazoline-2,4(1H,3H)-dione derivatives as dual c-Met/VEGFR-2-TK inhibitors
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2023.2189578
Abstract: Abstract The dual c-Met/vascular endothelial growth factor receptor 2 (VEGFR-2) TK inhibition is a good strategy to overcome therapeutic resistance to small molecules VEGFR-2 inhibitors. In this study, we designed 3-substituted quinazoline-2,4(1H,3H)-dione derivatives as dual… read more here.
Keywords: substituted quinazoline; dione derivatives; quinazoline dione; dual met ... See more keywords
Guanidine Derivatives of Quinazoline-2,4(1H,3H)-Dione as NHE-1 Inhibitors and Anti-Inflammatory Agents
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12101647
Abstract: Quinazolines are a rich source of bioactive compounds. Previously, we showed NHE-1 inhibitory, anti-inflammatory, antiplatelet, intraocular pressure lowering, and antiglycating activity for a series of quinazoline-2,4(1H,3H)-diones and quinazoline-4(3H)-one guanidine derivatives. In the present work, novel… read more here.
Keywords: derivatives quinazoline; anti inflammatory; quinazoline dione; guanidine derivatives ... See more keywords
Synthesis of a Pyrrolo[1,2-a]quinazoline-1,5-dione Derivative by Mechanochemical Double Cyclocondensation Cascade
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27175671
Abstract: N-heterocyclic compounds, such as quinazolinone derivatives, have significant biological activities. Nowadays, as the demand for environmentally benign, sustainable processes increases, the application of compounds from renewable sources, easily separable heterogeneous catalysts and efficient, alternative activation… read more here.
Keywords: cyclocondensation cascade; double cyclocondensation; quinazoline dione;
The First 5′-Phosphorylated 1,2,3-Triazolyl Nucleoside Analogues with Uracil and Quinazoline-2,4-Dione Moieties: A Synthesis and Antiviral Evaluation
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DOI: 10.3390/molecules27196214
Abstract: A series of 5′-phosphorylated (dialkyl phosphates, diaryl phosphates, phosphoramidates, H-phosphonates, phosphates) 1,2,3-triazolyl nucleoside analogues in which the 1,2,3-triazole-4-yl-β-D-ribofuranose fragment is attached via a methylene group or a butylene chain to the N-1 atom of the… read more here.
Keywords: nucleoside analogues; triazolyl nucleoside; uracil quinazoline; quinazoline dione ... See more keywords