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Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c07264
Abstract: Plant bacterial illnesses are common and cause dramatic damage to agricultural goods all over the world, yet there are few efficient bactericides to alleviate them at present. To discover novel antibacterial agents, two series of…
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Keywords:
design synthesis;
mechanism;
quinazolinone derivatives;
antibacterial evaluation ... See more keywords
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Published in 2020 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00596
Abstract: Naegleria fowleri and Balamuthia mandrillaris are protist pathogens that infect the central nervous system, causing primary amoebic meningoencephalitis and granulomatous amoebic encephalitis with mortality rates of over 95%. Quinazolinones and their derivatives possess a wide…
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Keywords:
quinazolinone derivatives;
eating amoebae;
derivatives novel;
aryl quinazolinone ... See more keywords
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Published in 2021 at "New Journal of Chemistry"
DOI: 10.1039/d0nj05450j
Abstract: In this study, three series of quinazolinone derivatives containing hydrazone structures were designed and synthesized. Bioactivity assays indicated that these compounds showed good antitumour activities towards human lung cancer cells (A549) and human prostate cancer…
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Keywords:
design synthesis;
structural units;
containing hydrazone;
biological activities ... See more keywords
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Published in 2017 at "Russian Journal of General Chemistry"
DOI: 10.1134/s1070363217090237
Abstract: Quinazolinylbenzoic acid 1 was used as a precursor for synthesis of many heterocyclic systems. Ethyl 4-[4-oxo-2-phenylquinazolin-3(4H)-yl]benzoate 2 upon reaction with hydrazine hydrate gave 4-[4-oxo-2-phenylquinazolin-3(4H)-yl]benzoate benzoylhydrazide 3. Compound 3 on treatment with 3-nitrobenzaldehyde, acetyl acetone, ethyl…
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Keywords:
quinazolinone derivatives;
biological activity;
characterization biological;
quinazolinone ... See more keywords
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Published in 2017 at "NANO"
DOI: 10.1142/s1793292017500023
Abstract: Polypyrrole/chitosan (PPC) spherical dark nanoparticles surrounded by shadow spheres were fabricated through in situ oxidative polymerization of pyrrole in presence of chitosan (CS) using ferric chloride (FeCl3) as oxidant and evaluated as a carrier for…
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Keywords:
quinazolinone derivatives;
core shell;
shell nanoparticles;
chitosan ... See more keywords
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Published in 2023 at "Current organic synthesis"
DOI: 10.2174/1570179420666230316094435
Abstract: Multiple potential drugs have been developed based on the heterocyclic molecules for the treatment of different symptoms. Among the existing heterocyclic molecules, quinazoline and quinazolinone derivatives have been found to exhibit extensive pharmacological and biological…
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Keywords:
anti tubercular;
quinazoline quinazolinone;
quinazolinone derivatives;
insight prospect ... See more keywords
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Published in 2018 at "Research in Pharmaceutical Sciences"
DOI: 10.4103/1735-5362.236838
Abstract: Nitrogen-rich heterocyclic compounds represent a unique class of chemicals with especial properties and have been modified to design novel pharmaceutically active compounds. In this study, a series of novel quinazolinone derivatives with substituted quinoxalindione were…
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Keywords:
quinazolinone derivatives;
novel quinazolinone;
cell lines;
cytotoxic evaluation ... See more keywords