Novel &bgr;‐carboline‐quinazolinone hybrids disrupt Leishmania donovani redox homeostasis and show promising antileishmanial activity
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2016.12.012
Abstract: Graphical abstract Figure. No Caption available. ABSTRACT Visceral Leishmaniasis is a deadly parasitic disease caused by Leishmania donovani. Paucity exists in the discovery of novel chemotherapeutics against Leishmaniasis. In this study, we synthesized a natural… read more here.
Keywords: bgr carboline; carboline quinazolinone; donovani; activity ... See more keywords
The antibacterial activity of quinazoline and quinazolinone hybrids.
Sign Up to like & getrecommendations! Published in 2022 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026622666220307144015
Abstract: Bacterial infections cause substantial morbidity and mortality across the world and pose serious threats to humankind. Drug resistance, especially multidrug resistance resulting from different defensive mechanisms in bacteria, is the leading cause of failure the… read more here.
Keywords: quinazolinone; quinazoline quinazolinone; antibacterial activity; activity quinazoline ... See more keywords