Efficient Buchwald–Hartwig and nitrene-mediated five-membered ring closure approaches to the total synthesis of quindoline. Unexpected direct conversion of a nitro group into a phosphazene
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DOI: 10.1039/d3ra02468g
Abstract: Two total syntheses of quindoline, which take place through the intermediacy of 3-nitroquinoline derivatives, are reported. The general synthetic sequence involves construction of the latter by mechanochemical condensation of benzaldehydes with 2-amino-nitrostyrene, followed either by… read more here.
Keywords: quindoline unexpected; nitrene mediated; buchwald hartwig; nitro group ... See more keywords