LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "quinidine" as a keyword



P‐Glycoprotein and Breast Cancer Resistance Protein Transporter Inhibition by Cyclosporine and Quinidine on the Pharmacokinetics of Oral Rimegepant in Healthy Subjects

Sign Up to like & get
recommendations! Published in 2022 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.1088

Abstract: Rimegepant (Nurtec ODT)—an orally administered, small‐molecule calcitonin gene–related peptide receptor antagonist indicated for the acute and preventive treatment of migraine—is a substrate for both the P‐glycoprotein and breast cancer resistance protein transporters in vitro. We… read more here.

Keywords: breast cancer; resistance protein; quinidine; cancer resistance ... See more keywords

8-Br-cGMP activates HSPB6 and increases the antineoplastic activity of quinidine in prostate cancer

Sign Up to like & get
recommendations! Published in 2024 at "Cell Death Discovery"

DOI: 10.1038/s41420-024-01853-3

Abstract: Heat shock protein family B [small] member 6 (HSPB6), widely found in various muscles, has been recently identified as a tumor suppressor gene. However, its role in prostate cancer remains unexplored. Herein, we investigated the… read more here.

Keywords: prostate; hspb6; prostate cancer; quinidine ... See more keywords

Modelling the effects of quinidine, disopyramide, and E-4031 on short QT syndrome variant 3 in the human ventricles.

Sign Up to like & get
recommendations! Published in 2017 at "Physiological measurement"

DOI: 10.1088/1361-6579/aa8695

Abstract: OBJECTIVE Short QT syndrome (SQTS) is an inherited cardiac channelopathy, but at present little information is available on its pharmacological treatment. SQT3 variant (linked to the inward rectifier potassium current I K1) of SQTS, results… read more here.

Keywords: effects quinidine; short syndrome; disopyramide 4031; quinidine ... See more keywords

6081Efficacy and limitations of quinidine therapy in patients with Brugada Syndrome

Sign Up to like & get
recommendations! Published in 2019 at "European Heart Journal"

DOI: 10.1093/eurheartj/ehz746.0125

Abstract: Quinidine at high-dose is used in patients with Brugada Syndrome (BrS), but its efficacy to prevent life-threatening arrhythmic events (LAE) in BrS is unproven and its use is limited by side effects. We assessed whether… read more here.

Keywords: brs; brs patients; patients brugada; quinidine ... See more keywords
Photo by nci from unsplash

Low‐Dose Quinidine Effectively Reduced Shocks in Brugada Syndrome Patients with an Implantable Cardioverter Defibrillator: A Chinese Case Series Report

Sign Up to like & get
recommendations! Published in 2017 at "Annals of Noninvasive Electrocardiology"

DOI: 10.1111/anec.12375

Abstract: Only implantable cardioverter defibrillators (ICD) have been proven to prevent sudden cardiac death (SCD) in patients with Brugada syndrome (BrS). However, ICD discharge, whether appropriate or inappropriate, leads to impaired quality of life and even… read more here.

Keywords: dose quinidine; low dose; quinidine effectively; quinidine ... See more keywords
Photo from wikipedia

Efficacy and Tolerability of Quinidine as Salvage Therapy for Monomorphic Ventricular Tachycardia in patients with Structural Heart Disease.

Sign Up to like & get
recommendations! Published in 2021 at "Journal of cardiovascular electrophysiology"

DOI: 10.1111/jce.15260

Abstract: INTRODUCTION Quinidine is an effective therapy for a subset of polymorphic ventricular tachycardia and ventricular fibrillation (VF) syndromes, however the efficacy of quinidine in scar related monomorphic ventricular tachycardia (MMVT) is unclear. METHODS AND RESULTS… read more here.

Keywords: monomorphic ventricular; ventricular tachycardia; structural heart; quinidine ... See more keywords

Rational quinidine dosage regimen for atrial fibrillation in Thoroughbred racehorses based on population pharmacokinetics

Sign Up to like & get
recommendations! Published in 2024 at "Frontiers in Veterinary Science"

DOI: 10.3389/fvets.2024.1454342

Abstract: Introduction Quinidine (QND) sulfate is an effective treatment for atrial fibrillation (AF) in horses, and several dosage regimens have been proposed to address its wide variability in response and potential adverse effects. The purpose of… read more here.

Keywords: dosage; quinidine; dosage regimen; quinidine concentrations ... See more keywords