Transition Metal‐Free One‐Pot Approach: Regioselective Synthesis of Pyrrolo[3,4‐b]quinolin‐1‐one Derivatives from o‐Alkynylquinoline‐3‐carbonitriles
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202400582
Abstract: A KOtBu‐promoted robust strategy has been described for the regioselective synthesis of pyrrolo[3,4‐b]quinolin‐1‐one and naphthyridin‐1(2H)‐one derivatives from o‐alkynylquinolinecarbonitriles in good to excellent yields. The reaction proceeds through in‐situ transformation of nitrile moiety into amide group… read more here.
Keywords: synthesis pyrrolo; one pot; pyrrolo quinolin; one derivatives ... See more keywords
Screening and identification of 3‐aryl‐quinolin‐2‐one derivatives as antiviral agents against influenza A
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28327
Abstract: Quinolin‐2‐one represents an important and valuable chemical motif that possesses a wide variety of biological activities; however, the anti‐influenza activities of quinolin‐2‐one‐containing compounds were rarely reported. Herein, we describe the screening and identification of 3‐aryl‐quinolin‐2‐one… read more here.
Keywords: identification aryl; aryl quinolin; quinolin one; antiviral agents ... See more keywords
Novel quinolin-2(1H)-one analogous as potential fungicides targeting succinate dehydrogenase: design, synthesis, inhibitory evaluation and molecular modeling.
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.7332
Abstract: BACKGROUND Succinate dehydrogenase is an important target of fungicides. Succinate dehydrogenase inhibitors have widely been used to combat destructive plant pathogenic fungi because they possess efficient and broad-spectrum antifungal activities and as well as unique… read more here.
Keywords: antifungal activities; one analogous; quinolin one; novel quinolin ... See more keywords
Design, synthesis and pharmacological evaluation of new 3-(1H-benzimidazol-2-yl)quinolin-2(1H)-one derivatives as potential antitumor agents.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.07.066
Abstract: A series of new 3-(1H-benzimidazol-2-yl)quinolin-2(1H)-one derivatives (5a1-5d6) were designed and synthesized as antitumor agents. In vitro antitumor assay results showed that some compounds exhibited moderate to high inhibitory activity against HepG2, SK-OV-3, NCI-H460 and BEL-7404 tumor… read more here.
Keywords: benzimidazol quinolin; one derivatives; quinolin one; antitumor agents ... See more keywords
Synthesis, spectral, photoluminescence, DFT studies and bioassay of new Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) complexes of 1-ethyl-4-hydroxy-3-(nitroacetyl) quinolin-2(1H)-one
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2018.04.023
Abstract: Abstract The complexation between 1-ethyl-4-hydroxy-3-(nitroacetyl)quinolin-2(1H)-one, H2L with iron(III), cobalt(II), nickel(II), copper(II) and zinc(II) has been accomplished. The structure of the resulting complexes has been elucidated through elemental analyses, FT-IR,1H NMR, electronic, mass spectra, powder XRD,… read more here.
Keywords: nitroacetyl quinolin; hydroxy nitroacetyl; quinolin one; ethyl hydroxy ... See more keywords
Three-Component Cyclization/Haloazidation of Bicyclo[1.1.0]butane-1-carboxamides: Construction of Halogenated Spiro[cyclobutane-1,3'-quinolin]-2'-one Derivatives.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c03545
Abstract: A new BCB-type substrate to assemble halogenated spiro[cyclobutane-1,3'-quinolin]-2'-one derivatives via a radical cascade strain-release cyclization reaction has been successfully developed. The reaction features broad substrate scope, mild reaction conditions, and separated diastereomers. Importantly, the reaction… read more here.
Keywords: spiro cyclobutane; halogenated spiro; cyclobutane quinolin; one derivatives ... See more keywords
The synthesis, biological evaluation and fluorescence study of chromeno[4,3-b]pyridin/quinolin-one derivatives, the backbone of natural product polyneomarline C scaffolds: a brief review
Sign Up to like & getrecommendations! Published in 2021 at "New Journal of Chemistry"
DOI: 10.1039/d0nj04761a
Abstract: Coumarins (natural, as well as synthetic) are an important class of heterocycles having immense potential for industrial and medicinal applications. Coumarin-fused heterocycles, mainly pyridine or quinoline, possess a plethora of biological attributes such as anti-bacterial,… read more here.
Keywords: pyridin quinolin; fluorescence; quinolin one; one derivatives ... See more keywords
8,8′-(Benzo[c][1,2,5]thiadiazole-4,7-diyl)bis(quinolin-4(1H)-one): a twisted photosensitizer with AIE properties
Sign Up to like & getrecommendations! Published in 2021 at "RSC Advances"
DOI: 10.1039/d1ra06263h
Abstract: A new benzothiadiazole (BTZ) luminogen is prepared via the Suzuki–Miyaura Pd-catalysed C–C cross-coupling of 8-iodoquinolin-4(1H)-one and a BTZ bispinacol boronic ester. read more here.
Keywords: thiadiazole diyl; quinolin one; benzo thiadiazole; bis quinolin ... See more keywords