Synthesis of a natural quinoline alkaloid isolated from the deep-sea-derived fungus and its potential as a therapeutic for Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2022.2104259
Abstract: Abstract 2-(Quinoline-8-carboxamido)benzoic acid (2-QBA; 1) is a natural quinoline alkaloid isolated from the deep-sea-derived fungus Aspergillus sp. SCSIO06786. Alkaloid 1 was synthesized by an amidation reaction of 8-quinolinecaroxylic acid with methyl anthranilate, followed by hydrolysis.… read more here.
Keywords: quinoline; quinoline alkaloid; parkinson disease; natural quinoline ... See more keywords
Total synthesis of pyrrolo[2,3-c]quinoline alkaloid: trigonoine B
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DOI: 10.3762/bjoc.17.62
Abstract: The first total synthesis of the pyrrolo[2,3-c]quinoline alkaloid trigonoine B (1) was accomplished via a six-step sequence involving the construction of an N-substituted 4-aminopyrrolo[2,3-c]quinoline framework via electrocyclization of 2-(pyrrol-3-yl)benzene containing a carbodiimide moiety as a… read more here.
Keywords: synthesis pyrrolo; pyrrolo quinoline; quinoline alkaloid; total synthesis ... See more keywords