Design, synthesis, and molecular docking study of novel quinoline‐based bis‐chalcones as potential antitumor agents
Sign Up to like & getrecommendations! Published in 2021 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202100094
Abstract: A novel series of quinoline‐based symmetrical and unsymmetrical bis‐chalcones was synthesized via a Claisen–Schmidt condensation reaction between 3‐formyl‐quinoline/quinolone derivatives with acetone or arylidene acetones, respectively, by using KOH/MeOH/H2O as a reaction medium. Twelve of the… read more here.
Keywords: design synthesis; bis chalcones; quinoline; bis ... See more keywords
Microwave Assisted Synthesis and Antimicrobial Potential of Quinoline-Based 4-Hydrazide-Hydrazone Derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Heterocyclic Chemistry"
DOI: 10.1002/jhet.3050
Abstract: The World Academy of Sciences (TWAS) was gratefully acknowledged by OOA for the sponsorship of this present work under the TWAS Research Grant for Individual Scientists in Basic Sciences Programme (grant no.: 14-069 RG/CHE/AF/AC_1). read more here.
Keywords: antimicrobial potential; microwave assisted; synthesis antimicrobial; assisted synthesis ... See more keywords
Designing new quinoline-based organic photosensitizers for dye-sensitized solar cells (DSSC): a theoretical investigation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-019-3958-y
Abstract: In this work, 27 new quinoline-derivative dyes were proposed, and their geometries, electronic structures, and absorption spectra were investigated using density functional theory (DFT) calculations. An important feature found in most of the new compounds… read more here.
Keywords: dye sensitized; new quinoline; sensitized solar; designing new ... See more keywords
Relay detection of Zn2+ and S2− by a quinoline-based fluorescent chemosensor in aqueous media and zebrafish
Sign Up to like & getrecommendations! Published in 2019 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2019.02.027
Abstract: Abstract A new quinoline-based fluorescent chemosensor MDCQA was designed and synthesized for the relay sensing of Zn2+ and S2−. MDCQA showed turn-on fluorescence toward Zn2+, and the resulting complex was able to detect S2− among… read more here.
Keywords: based fluorescent; quinoline based; zn2; fluorescent chemosensor ... See more keywords
A quinoline-based FtsZ inhibitor for the study of antimicrobial activity and synergistic effects with β-lactam antibiotics.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmacological sciences"
DOI: 10.1016/j.jphs.2018.07.005
Abstract: The antibacterial activity and the synergistic effect with β-lactam antibiotics of a new 1-methylquinolinium iodide derivative were investigated. The experimental results indicate that the compound possesses a strong antibacterial activity against a panel of bacteria… read more here.
Keywords: ftsz; lactam antibiotics; activity synergistic; compound ... See more keywords
Quinoline based colorimetric and “turn-off” fluorescent chemosensor for phosgene sensing in solution and vapor phase
Sign Up to like & getrecommendations! Published in 2021 at "Microchemical Journal"
DOI: 10.1016/j.microc.2021.106334
Abstract: Abstract Phosgene (COCl2) is a kind of extreme poisonous and colorless gas, causing many serious health problems. It’s an urgent requirement to develop a convenient and efficient analytical methods for detection of phosgene in environmental… read more here.
Keywords: fluorescent chemosensor; turn; phosgene; quinoline based ... See more keywords
Selective and sensitive detection of Fe3+ ions using quinoline-based fluorescent chemosensor: Experimental and DFT study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.05.044
Abstract: Abstract A new quinoline-based chemosensor, 1,3-dioxoisoindolin-2-yl quinoline-2-carboxylate (DQC) was synthesized and characterized by ESI-MS, 1H NMR, 13C NMR and FT-IR. The binding ability of DQC towards different metal ions was investigated by UV–visible and fluorescence… read more here.
Keywords: chemosensor; dft study; fe3; dqc ... See more keywords
New quinoline-based BODIPYs as EGFR/VEGFR-2 inhibitors: Molecular docking, DFT and in vitro cytotoxicity on HeLa cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131312
Abstract: Abstract This paper reports quinoline-based BODIPYs as potential EGFR/VEGFR-2 inhibitors and their anticancer activities against Hela cells. Lipinski's drug likeness of compounds 1-3 was predicted revealing that they might exhibit promising physicochemical properties for oral… read more here.
Keywords: egfr vegfr; based bodipys; hela cells; vegfr ... See more keywords
Quinoline-based ratiometric fluorescent probe for detection of physiological pH changes in aqueous solution and living cells.
Sign Up to like & getrecommendations! Published in 2019 at "Talanta"
DOI: 10.1016/j.talanta.2018.09.026
Abstract: Herein, a novel quinoline-based fluorescent probe DQPH has been developed for ratiometric detection of subtle pH fluctuation in biosystem. Upon altering the pH from 4.50 to 9.00, the emission spectra exhibit a large hypsochromic shift… read more here.
Keywords: fluorescent probe; detection; based ratiometric; probe ... See more keywords
Effect of a newly synthesized quinoline-based compound (PPQ-8) on murine schistosomiasis mansoni.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of helminthology"
DOI: 10.1017/s0022149x2000005x
Abstract: Schistosomiasis represents a public health problem and praziquantel is the only drug used for treatment of all forms of the disease. Thus, the development of new anti-schistosomal agents is of utmost importance to increase the… read more here.
Keywords: schistosomiasis; based compound; quinoline based; ppq ... See more keywords
Quinoline-Based Photolabile Protection Strategy Facilitates Efficient Protein Assembly.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c10324
Abstract: Native chemical ligation (NCL) provides a powerful solution to assemble proteins with precise chemical features, which enables a detailed investigation of the protein structure-function relationship. As an extension to NCL, the discovery of desulfurization and… read more here.
Keywords: strategy; protection; protein assembly; protein ... See more keywords