Articles with "quinoline carboxamides" as a keyword



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Cu-Catalyzed Coupling of O-Acyl Oximes with Isatins: Domino Rearrangement Strategy for Direct Access to Quinoline-4-Carboxamides by C-N Bond Cleavage

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Published in 2018 at "European Journal of Organic Chemistry"

DOI: 10.1002/ejoc.201800501

Abstract: A mild domino rearrangement strategy for the direct access to substituted quinoline‐4‐carboxamides has been developed. This copper‐catalyzed coupling reaction of O‐acyl oximes with isatins in the presence of molecular oxygen as the sole oxidizing agent… read more here.

Keywords: strategy direct; quinoline carboxamides; domino rearrangement; direct access ... See more keywords
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Isocyanide Reactions Toward the Synthesis of 3-(Oxazol-5-yl)Quinoline-2-Carboxamides and 5-(2-Tosylquinolin-3-yl)Oxazole

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Published in 2019 at "Frontiers in Chemistry"

DOI: 10.3389/fchem.2019.00433

Abstract: A palladium-catalyzed three-component reaction between 5-(2-chloroquinolin-3-yl) oxazoles, isocyanides, and water to yield 3-(oxazol-5-yl)quinoline-2-carboxamides is described. Interestingly, sulfonylation occurred when the same reaction was performed with toluenesulfonylmethyl isocyanide (TosMIC) as an isocyanide source. The reaction with… read more here.

Keywords: isocyanide reactions; oxazol quinoline; synthesis oxazol; quinoline carboxamides ... See more keywords