ZnCl2 supported on Fe3O4@SiO2 core–shell nanocatalyst for the synthesis of quinolines via Friedländer synthesis under solvent-free condition
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DOI: 10.1002/aoc.3566
Abstract: A magnetic nanocatalyst of Fe3O4@SiO2/ZnCl2 was prepared by supporting ZnCl2 on silica-coated magnetic nanoparticles of Fe3O4. This recoverable catalyst was used for the synthesis of quinolines via Friedlander synthesis from 2-aminoaryl ketones and α-methylene ketones… read more here.
Keywords: fe3o4 sio2; zncl2; quinolines via; solvent free ... See more keywords
Synthesis of novel 3-(quinazol-2-yl)-quinolines via SNAr and aluminum chloride-induced (hetero) arylation reactions and biological evaluation as proteasome inhibitors
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DOI: 10.1016/j.tetlet.2020.151805
Abstract: Abstract A new series of 3-(quinazol-2-yl)-quinolines was synthesized by SNAr reaction from easily prepared 4-chloro-2-(2-chloroquinolin-3-yl)quinazolines and a range of phenols and thiophenol as nucleophiles. The AlCl3-mediated C C bond formation was also successfully exploited to… read more here.
Keywords: quinazol; synthesis novel; proteasome; novel quinazol ... See more keywords
Photocatalytic Synthesis of Quinolines via Povarov Reaction under Oxidant-Free Conditions.
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DOI: 10.1021/acs.orglett.1c04287
Abstract: We describe here an approach for synthesizing quinolines either from N-alkyl anilines or from anilines and aldehydes. A dual-catalyst system consisting of a photocatalyst and a proton reduction cocatalyst is employed. Without the use of… read more here.
Keywords: photocatalytic synthesis; povarov reaction; via povarov; quinolines via ... See more keywords
Direct Synthesis of 2,3-Diaroyl Quinolines and Pyridazino[4,5- b]quinolines via an I2-Promoted One-Pot Multicomponent Reaction.
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DOI: 10.1021/acs.orglett.9b00685
Abstract: The first synthesis of 2,3-diaroyl quinolines via a formal [3 + 2 + 1] cycloaddition of enaminones, aryl methyl ketones, and aryl amines is disclosed. This reaction efficiently affords a 1,4-dicarbonyl scaffold, which is a… read more here.
Keywords: diaroyl quinolines; one pot; quinolines via; synthesis diaroyl ... See more keywords