Discovery of N-quinazolinone-4-hydroxy-2-quinolone-3-carboxamides as DNA gyrase B-targeted antibacterial agents
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DOI: 10.1080/14756366.2022.2084088
Abstract: Abstract Emerging drug resistance is generating an urgent need for novel and effective antibiotics. A promising target that has not yet been addressed by approved antibiotics is the bacterial DNA gyrase subunit B (GyrB), and… read more here.
Keywords: hydroxy quinolone; targeted antibacterial; dna gyrase; quinolone carboxamides ... See more keywords