Design, synthesis and biological activity of 1,4-quinone moiety attached to betulin derivatives as potent DT-diaphorase substrate.
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DOI: 10.1016/j.bioorg.2020.104478
Abstract: In this research, betulin derivatives were bonded to the 1,4-quinone fragment by triazole linker. Furthermore, the enzymatic assay used has shown that these compounds are a good DT-diaphorase (NQO1) substrates as evidenced by increasing enzymatic… read more here.
Keywords: betulin derivatives; quinone moiety; activity;