Identification and Characterization of Natural and Semisynthetic Quinones as Aurora Kinase Inhibitors.
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DOI: 10.1021/acs.jnatprod.1c01222
Abstract: Aurora kinases (Aurora A, B, and C) are a family of serine/threonine kinases that play critical roles during mitotic initiation and progression. Aurora A and B kinases are ubiquitously expressed, and their overexpression and/or amplification… read more here.
Keywords: aurora kinase; kinase inhibitors; kinase; quinones aurora ... See more keywords