A New Method for the Synthesis of Substituted 8,9,10,11-Tetrahydroindolo[1,2-a]Quinoxalin-6(5H)-Ones
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DOI: 10.1007/s10593-017-2090-0
Abstract: The reaction of 1-(cyclohexen-1-yl)pyrrolidines with 3-(α-chlorobenzyl)quinoxalin-2(1H)-ones resulted in the formation of 8,9,10,11-tetrahydroindolo[1,2-a]quinoxalin-6(5H)-ones via a tandem sequence of Stork enamine alkylation and intramolecular annulation. Oxidative dehydrogenation gave indolo[1,2-a]quinoxalin-6(5H)-one. read more here.
Keywords: new method; synthesis substituted; quinoxalin ones; tetrahydroindolo quinoxalin ... See more keywords
Reductive acid-catalyzed rearrangement of 3-(2-nitrobenzyl)quinoxalin-2(1Н)-ones in the presence of Na2S2O4 – effective method for the synthesis of 2-(indol-2-yl)benzimidazoles
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DOI: 10.1007/s10593-017-2166-x
Abstract: An effective one-step method is proposed for the synthesis of 2-(indol-2-yl)benzimidazoles from 3-(2-nitrobenzyl)quinoxalin-2(1Н)-ones without using metal catalysts and reagents. This method is based on the Mamedov rearrangement of 3-(2-aminobenzyl)quinoxalin-2(1Н)-ones, formed in situ by the action… read more here.
Keywords: synthesis indol; nitrobenzyl quinoxalin; method; quinoxalin ones ... See more keywords
Methods for the synthesis of quinoxalin-2-ones (microreview)
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DOI: 10.1007/s10593-020-02692-7
Abstract: In this microreview, recent methods for the synthesis of quinoxalin-2-ones are surveyed. Microreview covers the selected works published in 2015–2019. read more here.
Keywords: quinoxalin ones; ones microreview; methods synthesis; synthesis quinoxalin ... See more keywords
Rapid alkenylation of quinoxalin-2(1H)-ones enabled by the sequential Mannich-type reaction and solar photocatalysis
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DOI: 10.1016/j.cclet.2021.04.016
Abstract: Abstract Herein, a rapid alkenylation of quinoxalin-2(1H)-ones enabled by a combination of Mannich-type reaction and solar photocatalysis is demonstrated. A wide range of functional groups are compatible, affording the corresponding products in moderate-to-good yields. Control… read more here.
Keywords: ones enabled; quinoxalin ones; alkenylation quinoxalin; reaction ... See more keywords
Visible-light-initiated 4CzIPN catalyzed multi-component tandem reactions to assemble sulfonated quinoxalin-2(1H)-ones
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DOI: 10.1016/j.cclet.2021.08.036
Abstract: Abstract A mild and efficient photochemical multi-component tandem reaction of quinoxalin-2(1H)-ones, alkenes and sulfinic acids is reported. This tandem reaction could be conveniently carried out at room temperature by employing 4CzIPN as the metal-free photocatalyst… read more here.
Keywords: multi component; visible light; quinoxalin ones; component tandem ... See more keywords
Mn(OAc)3*2H2O promoted addition of arylboronic acids to quinoxalin-2-ones
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DOI: 10.1016/j.tetlet.2017.12.085
Abstract: Abstract A simple method has been developed for the synthesis of 3-aryl quinoxalin-2-one derivatives through an oxidative cross-coupling of arylboronic acids with quinoxalin-2-ones using a readily available oxidant Mn(III) acetate dihydrate. This method provides 3-aryl… read more here.
Keywords: 2h2o promoted; quinoxalin ones; arylboronic acids; acids quinoxalin ... See more keywords
Copper-Catalyzed Divergent C-H Functionalization Reaction of Quinoxalin-2(1H)-ones and Alkynes Controlled by N1-Substituents for the Synthesis of (Z)-Enaminones and Furo[2,3-b]quinoxalines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00454
Abstract: With control by N1-substituents, the switchable divergent C-H functionalization reaction of quinoxalin-2(1H)-ones is achieved for the synthesis of (Z)-enaminones and furo[2,3-b]quinoxalines using the combination of a copper catalyst and an oxidant. This new protocol features… read more here.
Keywords: divergent functionalization; functionalization reaction; reaction; reaction quinoxalin ... See more keywords
Photoredox-Catalyzed C-H Trideuteromethylation of Quinoxalin-2(1H)-ones with CDCl3 as the "CD3" source.
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DOI: 10.1021/acs.orglett.2c02439
Abstract: Herein, readily available and inexpensive CDCl3 was first identified as a new trideuteromethylation reagent under photoredox-catalyzed conditions. Thus, a facile photocatalytic protocol for the C-H trideuteromethylation of quinoxalin-2(1H)-one was achieved. This operationally straightforward transformation displays… read more here.
Keywords: catalyzed trideuteromethylation; quinoxalin ones; trideuteromethylation; trideuteromethylation quinoxalin ... See more keywords
Visible-Light-Initiated Difunctionalization of Quinoxalin-2(1H)-ones with Acyloxy Nitroso Compounds.
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DOI: 10.1021/acs.orglett.2c02703
Abstract: Herein, a photoinitiated radical relay reaction of quinoxalin-2(1H)-ones, with acyloxy nitroso compounds as a source of radicals, is described. Although the C-H functionalization of quinoxalin-2(1H)-ones has been investigated, its difunctionalization, the simultaneous construction of C-C… read more here.
Keywords: acyloxy nitroso; difunctionalization; ones acyloxy; quinoxalin ones ... See more keywords
Chemoselective N-H or C-2 Arylation of Indole-2-carboxamides: Controllable Synthesis of Indolo[1,2- a]quinoxalin-6-ones and 2,3'-Spirobi[indolin]-2'-ones.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b02197
Abstract: Novel methods involving the chemoselective N-H or C-2 arylation for the synthesis of indolo[1,2- a]quinoxalin-6-ones and 2,3'-spirobi[indolin]-2'-ones starting from indole-2-carboxamides were developed. When reactions were carried out using ZnI2 as catalyst and Ag2CO3 as oxidant,… read more here.
Keywords: quinoxalin ones; indolo quinoxalin; spirobi indolin; indolin ones ... See more keywords
Divergent g-C3N4-catalyzed Reactions of Quinoxalin-2(1H)-ones with N-Aryl Glycines under Visible Light: Solvent-Controlled Hydroaminomethylation and Annulation
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DOI: 10.1021/acssuschemeng.0c02289
Abstract: An effective and simple visible light-induced heterogeneous g-C3N4-catalyzed decarboxylative reaction of quinoxalin-2(1H)-ones with N-aryl glycines was developed. When the reaction was performed in... read more here.
Keywords: c3n4 catalyzed; ones aryl; aryl glycines; visible light ... See more keywords