N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships, and in Vitro Pharmacology.
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DOI: 10.2210/pdb6fz4/pdb
Abstract: Among the ionotropic glutamate receptors, the physiological role of kainate receptors is less well understood. Although ligands with selectivity toward the kainate receptor subtype GluK1 are available, tool compounds with selectivity at the remaining kainate… read more here.
Keywords: kainate receptor; quinoxaline diones; affinity; structure ... See more keywords