Discovery of new quinoxaline-2(1H)-one-based anticancer agents targeting VEGFR-2 as inhibitors: Design, synthesis, and anti-proliferative evaluation.
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DOI: 10.1016/j.bioorg.2021.105105
Abstract: VEGF/VEGFR2 pathway is the crucial therapeutic target in the treatment of cancer. So that, a new series of quinoxaline-2(1H)-one derivatives were designed and synthesized. The synthesized compounds were tested against three human cancer cell lines… read more here.
Keywords: anti proliferative; hct 116; cell lines; quinoxaline one ... See more keywords