Non-IDH1-R132H IDH1/2 mutations are associated with increased DNA methylation and improved survival in astrocytomas, compared to IDH1-R132H mutations
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DOI: 10.1007/s00401-021-02291-6
Abstract: Somatic mutations in the isocitrate dehydrogenase genes IDH1 and IDH2 occur at high frequency in several tumour types. Even though these mutations are confined to distinct hotspots, we show that gliomas are the only tumour… read more here.
Keywords: r132h; r132h idh1; idh1 r132h; dna methylation ... See more keywords