R132 mutations in canine isocitrate dehydrogenase 1 (IDH1) lead to functional changes
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DOI: 10.1007/s11259-017-9707-8
Abstract: Glioma is the second most common intracranial neoplasia in dogs, but the pathogenic mechanisms remain unclear. In humans, isocitrate dehydrogenase 1 (IDH1) is frequently mutated in gliomas. Although almost all human IDH1 mutations have been… read more here.
Keywords: r132h; isocitrate dehydrogenase; dehydrogenase idh1; r132s ... See more keywords