Gain-of-Function Mutation in Ryanodine Receptor Type 1 Modulates Murine Thymocyte Calcium Signaling and Autoimmune Response in Mice
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DOI: 10.1016/j.bpj.2016.11.559
Abstract: Gain-of-function mutations in gene encoding ryanodine receptor type 1 (RyR1), an endo/sarcoplasmic reticulum Ca2+ release channel, are linked to a variety of skeletal muscular disorders. Other tissues, including cells of the immune system, have been… read more here.
Keywords: r163c mice; mutation; gain function; mice ... See more keywords