TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk.
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DOI: 10.1002/hep.32802
Abstract: BACKGROUND AND AIMS Major genomic drivers of hepatocellular carcinoma (HCC) are nowadays well recognized, although models to establish their roles in human HCC initiation remain scarce. Here, we used human liver organoids in experimental systems to… read more here.
Keywords: r249s mutation; hcc; liver organoids; tp53 ... See more keywords