What 20 years of research has taught us about the TP53 p.R337H mutation
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DOI: 10.1002/cncr.33143
Abstract: The p53 tumor suppressor transcriptionally regulates a myriad of genes involved in cell cycle control, DNA repair, cell survival, and cell metabolism and represents one of the most well‐studied inhibitors of tumorigenesis. Since the discovery… read more here.
Keywords: cancer; r337h mutation; tp53 r337h; tp53 ... See more keywords
Frequency of the TP53 p.R337H mutation in a Brazilian cohort of pediatric patients with solid tumors
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DOI: 10.1007/s11033-020-05655-5
Abstract: TP53 p.R337H germline mutation is highly prevalent in the Southern region of Brazil. We sought to investigate TP53 p.R337H mutation in pediatric tumor samples from a population settled in a geographic area of high prevalence… read more here.
Keywords: frequency tp53; r337h mutation; tp53 r337h; mutation ... See more keywords