Alzheimer's disease‐associated R47H TREM2 increases, but wild‐type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24318
Abstract: Triggering receptor on myeloid cells 2 (TREM2) is an innate immune receptor, upregulated on the surface of microglia associated with amyloid plaques in Alzheimer's disease (AD). Individuals heterozygous for the R47H variant of TREM2 have… read more here.
Keywords: r47h trem2; trem2; phagocytosis; neuronal loss ... See more keywords