Articles with "r525h" as a keyword



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High-Throughput Screening to Identify Inhibitors of DEAD Box Helicase DDX41

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Published in 2017 at "SLAS Discovery"

DOI: 10.1177/2472555217705952

Abstract: The human DEAD (Asp–Glu–Ala–Asp) box protein DDX41, a member of the DEXDc helicase family, has nucleic acid–dependent ATPase and RNA and DNA translocase and unwinding activities. DDX41 is affected by somatic mutations in sporadic cases… read more here.

Keywords: r525h; ddx41; high throughput; helicase ... See more keywords