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R534C mutation in hERG causes a trafficking defect in iPSC-derived cardiomyocytes from patients with type 2 long QT syndrome

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1 Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-55837-w

Abstract: Patient-specific cardiomyocytes obtained from induced pluripotent stem cells (CM-iPSC) offer unprecedented mechanistic insights in the study of inherited cardiac diseases. The objective of this work was to study a type 2 long QT syndrome (LQTS2)-associated… read more here.

Keywords: r534c mutation; long syndrome; herg; ipsc ... See more keywords