TJ-M2010-5, a novel MyD88 inhibitor, corrects R848-induced lupus-like immune disorders of B cells in vitro.
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DOI: 10.1016/j.intimp.2020.106648
Abstract: B cell hyperactivities are involved in the development of systemic lupus erythematosus (SLE). Toll-like receptor 7 (TLR7) in the B cells plays a pivotal role in the pathogenesis of SLE. Previous studies have focused on… read more here.
Keywords: m2010 novel; lupus like; r848 induced; lupus ... See more keywords