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   Articles with "rab" as a keyword



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The TRAPP complexes: discriminating GTPases in context

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14557

Abstract: Correct localization of Rab GTPases in cells is critical for proper function in membrane trafficking. Guanine‐nucleotide exchange factors (GEFs) act as the primary determinants of Rab localization by activating and stabilizing their Rab substrates on… read more here.

Keywords: trapp complexes; rab; complexes discriminating; discriminating gtpases ... See more keywords
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Localization and functional analysis of the insect-specific RabX4 in the brain of Bombyx mori.

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recommendations! Published in 2017 at "Archives of insect biochemistry and physiology"

DOI: 10.1002/arch.21404

Abstract: Rab proteins are small monomeric GTPases/GTP-binding proteins, which form the largest branch of the Ras superfamily. The different Rab GTPases are localized to the cytosolic face of specific intracellular membranes, where they function as regulators… read more here.

Keywords: rab; bombyx mori; insect specific; rabx4 ... See more keywords
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TPI1‐reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis

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recommendations! Published in 2021 at "Journal of Extracellular Vesicles"

DOI: 10.1002/jev2.12135

Abstract: Abstract Rab GTPases are major mediators that ensure the proper spatiotemporal regulation of intracellular trafficking. Functional impairment and altered expression of Rab proteins have been revealed in various human cancers. There is an emerging evidence… read more here.

Keywords: extracellular vesicles; rab; hcc; aerobic glycolysis ... See more keywords
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Unselective ground-state blockade of Rydberg atoms for implementing quantum gates

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recommendations! Published in 2021 at "Frontiers of Physics"

DOI: 10.1007/s11467-021-1104-7

Abstract: A dynamics regime of Rydberg atoms, unselective ground-state blockade (UGSB), is proposed in the context of Rydberg antiblockade (RAB), where the evolution of two atoms is suppressed when they populate in an identical ground state.… read more here.

Keywords: rydberg; rab; ground state; rydberg atoms ... See more keywords
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Dual Arginine Recognition of LRRK2 phosphorylated Rab GTPases.

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recommendations! Published in 2021 at "Biophysical journal"

DOI: 10.1016/j.bpj.2021.03.030

Abstract: Parkinson's disease-associated LRRK2 is a multi-domain Ser/Thr kinase that phosphorylates a subset of Rab GTPases to control their effector functions. Rab GTPases are the prime regulators of membrane trafficking in eukaryotic cells. Rabs exert their… read more here.

Keywords: rab; rab gtpases; dual arginine; lrrk2 phosphorylated ... See more keywords
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Rab regulation by GEFs and GAPs during membrane traffic.

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recommendations! Published in 2019 at "Current opinion in cell biology"

DOI: 10.1016/j.ceb.2019.03.004

Abstract: Rab GTPases and their regulatory proteins play a crucial role in vesicle-mediated membrane trafficking. During vesicle membrane tethering Rab GTPases are activated by GEFs (guanine nucleotide exchange factors) and then inactivated by GAPs (GTPase activating… read more here.

Keywords: traffic; gefs gaps; rab; vesicle ... See more keywords
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Application of different modifiers for improvement of chemical characterization and physical-rheological parameters of reclaimed asphalt binder

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recommendations! Published in 2019 at "Construction and Building Materials"

DOI: 10.1016/j.conbuildmat.2019.01.086

Abstract: Abstract Bitumen extracted from reclaimed asphalt pavement (RAP) materials is known as reclaimed asphalt binder (RAB). Many studies have been conducted to evaluate effect of the rejuvenating agents in physical-rheological and chemical properties of the… read more here.

Keywords: rab; chemical; reclaimed asphalt; binder ... See more keywords
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Role of Rab GTPases in Alzheimer's Disease.

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recommendations! Published in 2019 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.8b00387

Abstract: Alzheimer's disease (AD) comprises two major pathological hallmarks: extraneuronal deposition of β-amyloid (Aβ) peptides ("senile plaques") and intraneuronal aggregation of the microtubule-associated protein tau ("neurofibrillary tangles"). Aβ is derived from sequential cleavage of the β-amyloid… read more here.

Keywords: alzheimer disease; rab; rab gtpases; role rab ... See more keywords
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Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1

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recommendations! Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-020-20702-2

Abstract: Legionella pneumophila infects eukaryotic cells by forming a replicative organelle – the Legionella containing vacuole. During this process, the bacterial protein DrrA/SidM is secreted and manipulates the activity and post-translational modification (PTM) states of the… read more here.

Keywords: rab; legionella; rab1 ampylation; drra ... See more keywords
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S1P1 receptor phosphorylation, internalization, and interaction with Rab proteins: effects of sphingosine 1-phosphate, FTY720-P, phorbol esters, and paroxetine

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recommendations! Published in 2018 at "Bioscience Reports"

DOI: 10.1042/bsr20181612

Abstract: Sphingosine 1-phosphate (S1P) and FTY720-phosphate (FTYp) increased intracellular calcium in cells expressing S1P1 mCherry-tagged receptors; the synthetic agonist was considerably less potent. Activation of protein kinase C by phorbol myristate acetate (PMA) blocked these effects.… read more here.

Keywords: protein; rab; s1p1 receptor; interaction ... See more keywords
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Rabifier2: an improved bioinformatic classifier of Rab GTPases

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recommendations! Published in 2017 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btw654

Abstract: Summary: The Rab family of small GTPases regulates and provides specificity to the endomembrane trafficking system; each Rab subfamily is associated with specific pathways. Thus, characterization of Rab repertoires provides functional information about organisms and… read more here.

Keywords: improved bioinformatic; rab; rab gtpases; rabifier2 improved ... See more keywords