Overexpression of synaptic vesicle protein Rab GTPase 3C promotes vesicular exocytosis and drug resistance in colorectal cancer cells
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13378
Abstract: Rab GTPase 3C (RAB3C) is a peripheral membrane protein that is involved in membrane trafficking (vesicle formation) and cell movement. Recently, researchers have noted the exocytosis of RAB proteins, and their dysregulation is correlated with… read more here.
Keywords: rab gtpase; resistance; drug resistance; rab3c ... See more keywords
The RAB GTPase RAB18 modulates macroautophagy and proteostasis.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.03.112
Abstract: Macroautophagy is a conserved degradative pathway and its deterioration is linked to disturbances in cellular proteostasis and multiple diseases. Here, we show that the RAB GTPase RAB18 modulates autophagy in primary human fibroblasts. The knockdown… read more here.
Keywords: rab gtpase; proteostasis; rab18; rab18 modulates ... See more keywords
Protein kinase A participates in hyphal and appressorial development by targeting Efg1‐mediated transcription of a Rab GTPase in Setosphaeria turcica
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Plant Pathology"
DOI: 10.1111/mpp.13253
Abstract: Abstract The cyclic adenosine monophosphate (cAMP) signalling pathway plays an important role in the regulation of the development and pathogenicity of filamentous fungi. cAMP‐dependent protein kinase A (PKA) is the conserved element downstream of cAMP,… read more here.
Keywords: protein kinase; setosphaeria turcica; transcription; development ... See more keywords