Regulation of the small GTPase Rab1 function by a bacterial glucosyltransferase
Sign Up to like & getrecommendations! Published in 2018 at "Cell Discovery"
DOI: 10.1038/s41421-018-0055-9
Abstract: Posttranslational modification of key host proteins by virulence factors is an important theme in bacterial pathogenesis. A remarkable example is the reversible modifications of the small GTPase Rab1 by multiple effectors of the bacterial pathogen… read more here.
Keywords: glucosyltransferase; rab1; small gtpase; gtpase ... See more keywords
The Uso1 globular head interacts with SNAREs to maintain viability even in the absence of the coiled-coil domain.
Sign Up to like & getrecommendations! Published in 2023 at "eLife"
DOI: 10.7554/elife.85079
Abstract: Uso1/p115 and RAB1 tether ER-derived vesicles to the Golgi. Uso1/p115 contains a globular-head-domain (GHD), a coiled-coil (CC) mediating dimerization/tethering and a C-terminal region (CTR) interacting with golgins. Uso1/p115 is recruited to vesicles by RAB1. Genetic… read more here.
Keywords: rab1; e6k g540s; domain; ghd ... See more keywords