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   Articles with "rab10" as a keyword



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LncRNA EBLN3P promotes the progression of osteosarcoma through modifying the miR-224-5p/Rab10 signaling axis

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recommendations! Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-81641-6

Abstract: The treatment of patients with advanced-stage osteosarcoma represents a major challenge, with very few treatments currently approved. Although accumulating evidence has demonstrated the importance of lncRNAs in osteosarcoma, the current knowledge on the functional roles… read more here.

Keywords: ebln3p; rab10; 224 rab10; mir 224 ... See more keywords
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Circular RNA hsa_circ_0001658 regulates apoptosis and autophagy in gastric cancer through microRNA-182/Ras-related protein Rab-10 signaling axis

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2021.2024637

Abstract: ABSTRACT Gastric cancer (GC) is a tumor with high incidence and lack of early diagnostic markers. The aim of this study was to explore novel regulatory circular RNAs (circRNAs) in GC and their underlying mechanisms.… read more here.

Keywords: cell; rab10; circ; mir 182 ... See more keywords
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Behavioral and Transcriptome Profiling of Heterozygous Rab10 Knock-Out Mice

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recommendations! Published in 2023 at "eNeuro"

DOI: 10.1523/eneuro.0459-22.2023

Abstract: Abstract A central question in the field of aging research is to identify the cellular and molecular basis of neuroresilience. One potential candidate is the small GTPase, Rab10. Here, we used Rab10+/− mice to investigate… read more here.

Keywords: transcriptome profiling; profiling heterozygous; rab10; behavioral transcriptome ... See more keywords
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Inhibition of LRRK2-Rab10 Pathway Improves Secondary Brain Injury After Surgical Brain Injury in Rats

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recommendations! Published in 2021 at "Frontiers in Surgery"

DOI: 10.3389/fsurg.2021.749310

Abstract: Leucine-rich repeat kinase 2 (LRRK2) is considered as a potential target for the treatment of Parkinson's disease. This protein is expressed in the brain and has been associated with various diseases and lysosomal maintenance. Rab10… read more here.

Keywords: brain injury; lrrk2; rab10; surgical brain ... See more keywords
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RAB10 Interacts with ABCB4 and Regulates Its Intracellular Traffic

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recommendations! Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22137087

Abstract: ABCB4 (ATP-binding cassette subfamily B member 4) is an ABC transporter expressed at the canalicular membrane of hepatocytes where it ensures phosphatidylcholine secretion into bile. Genetic variations of ABCB4 are associated with several rare cholestatic… read more here.

Keywords: interacts abcb4; rab10; intracellular traffic; abcb4 regulates ... See more keywords
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Proper Balance of Small GTPase rab10 Is Critical for PGC Migration in Zebrafish

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recommendations! Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms222111962

Abstract: MicroRNAs (miRNAs) play important roles in post-transcriptional repression in nearly every biological process including germ cell development. Previously, we have identified a zebrafish germ plasm-specific miRNA miR-202-5p, which regulates PGC migration through targeting cdc42se1 to… read more here.

Keywords: migration zebrafish; rab10; migration; pgc migration ... See more keywords