Rab11 plays a key role in stellate cell differentiation via non-canonical Notch pathway in Malpighian tubules of Drosophila melanogaster.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental biology"
DOI: 10.1016/j.ydbio.2020.01.002
Abstract: Rab11, a member of Rab-GTPase family, and a marker of recycling endosomes have been reported to be involved in the differentiation of various tissues in Drosophila. Here we report a novel role of Rab11 in… read more here.
Keywords: rab11; non canonical; stellate; canonical notch ... See more keywords
Rab11-mediated recycling endosome role in nervous system development and neurodegenerative diseases
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DOI: 10.1080/00207454.2020.1761354
Abstract: Abstract Study: Membrane trafficking process is significant for the complex and precise regulatory of the nervous system. Rab11, as a small GTPase of the Rab superfamily, controls endocytic vesicular trafficking to the cell surface after… read more here.
Keywords: membrane trafficking; rab11; nervous system; neurodegenerative diseases ... See more keywords
Loss of endosomal recycling factor RAB11 coupled with complex regulation of MAPK/ERK/AKT signaling in postmortem spinal cord specimens of sporadic amyotrophic lateral sclerosis patients
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Brain"
DOI: 10.1186/s13041-019-0475-y
Abstract: Synaptic abnormalities, perturbed endosomal recycling mediated by loss of the small GTPase RAB11, and neuroinflammatory signaling have been associated with multiple neurodegenerative diseases including the motor neuron disease, amyotrophic lateral sclerosis (ALS). This is consistent… read more here.
Keywords: rab11; erk; pathology; mapk ... See more keywords
Rab11 is required for lysosome exocytosis through the interaction with Rab3a, Sec15 and GRAB
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DOI: 10.1242/jcs.246694
Abstract: ABSTRACT Lysosomes are dynamic organelles, capable of undergoing exocytosis. This process is crucial for several cellular functions, namely plasma membrane repair. Nevertheless, the molecular machinery involved in this process is poorly understood. Here, we identify… read more here.
Keywords: rab3a; rab11; lysosome exocytosis; required lysosome ... See more keywords
Respiratory syncytial virus ribonucleoproteins hijack microtubule Rab11 dependent transport for intracellular trafficking
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DOI: 10.1371/journal.ppat.1010619
Abstract: Respiratory syncytial virus (RSV) is the primary cause of severe respiratory infection in infants worldwide. Replication of RSV genomic RNA occurs in cytoplasmic inclusions generating viral ribonucleoprotein complexes (vRNPs). vRNPs then reach assembly and budding… read more here.
Keywords: syncytial virus; rab11; transport; rsv ... See more keywords
Oncogenic Pathways and Loss of the Rab11 GTPase Synergize To Alter Metabolism in Drosophila
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DOI: 10.1534/genetics.119.302137
Abstract: Colorectal cancer is a complex disease driven by well-established mutations such as APC and other yet to be identified pathways. The GTPase Rab11 regulates endosomal protein trafficking, and previously we showed that loss of Rab11… read more here.
Keywords: rab11; metabolism; loss rab11; cancer ... See more keywords
A Comprehensive Review on the Interaction Between the Host GTPase Rab11 and Influenza A Virus
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DOI: 10.3389/fcell.2018.00176
Abstract: This year marks the 100th anniversary of one of the deadliest pandemic outbreaks, commonly referred as the Spanish Flu, that was caused by influenza A virus (IAV). Since then, IAV has been in governmental agendas… read more here.
Keywords: rab11; iav; review; host ... See more keywords
Rab5 and Rab11 maintain hematopoietic homeostasis by restricting multiple signaling pathways in Drosophila
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DOI: 10.7554/elife.60870
Abstract: The hematopoietic system of Drosophila is a powerful genetic model for studying hematopoiesis, and vesicle trafficking is important for signal transduction during various developmental processes; however, its interaction with hematopoiesis is currently largely unknown. In… read more here.
Keywords: rab5 rab11; hematopoietic homeostasis; lamellocyte formation; rab11 ... See more keywords