Targeting the Lysosomal Degradation of Rab22a‐NeoF1 Fusion Protein for Osteosarcoma Lung Metastasis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202205483
Abstract: Rab22a‐NeoF fusion protein has recently been reported as a promising target for osteosarcoma lung metastasis. However, how this fusion protein is regulated in cells remains unknown. Here, using multiple screenings, it is reported that Rab22a‐NeoF1… read more here.
Keywords: rab22a neof1; osteosarcoma lung; fusion protein; rab22a ... See more keywords
Rab22a-NeoF1 fusion protein promotes osteosarcoma lung metastasis through its secretion into exosomes
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-020-00414-1
Abstract: It remains unknown for decades how some of the therapeutic fusion proteins positive in a small percentage of cancer cells account for patient outcome. Here, we report that osteosarcoma Rab22a-NeoF1 fusion protein, together with its… read more here.
Keywords: neof1 fusion; rab22a neof1; fusion; fusion protein ... See more keywords