RAB26-dependent autophagy protects adherens junctional integrity in acute lung injury
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DOI: 10.1080/15548627.2018.1476811
Abstract: ABSTRACT Microvascular barrier dysfunction is the central pathophysiological feature of acute lung injury (ALI). RAB26 is a newly identified small GTPase involved in the regulation of endothelial cell (EC) permeability. However, the mechanism behind this… read more here.
Keywords: acute lung; integrity; autophagy; lung injury ... See more keywords
Regulation on Toll-like Receptor 4 and Cell Barrier Function by Rab26 siRNA-loaded DNA Nanovector in Pulmonary Microvascular Endothelial Cells
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DOI: 10.7150/thno.17584
Abstract: The small GTPase Rab26 is involved in multiple processes, such as vesicle-mediated secretion and autophagy. However, the mechanisms and functions of Rab26 in the human pulmonary microvascular endothelial cells (HPMVECs) are not clear. In this… read more here.
Keywords: sirna loaded; microvascular endothelial; rab26 sirna; endothelial cells ... See more keywords