The absence of Rab27a accelerates the degradation of Melanophilin
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Dermatology"
DOI: 10.1111/exd.13840
Abstract: Melanophilin (Mlph) forms an interaction with Rab27a and the actin‐based motor protein MyosinVa (MyoVa) on mature melanosome membranes and the tripartite complex regulates melanosome transport in melanocytes. In this study, we found that Rab27a siRNA… read more here.
Keywords: degradation; melanophilin; rab27a; absence rab27a ... See more keywords
Versatile Role of Rab27a in Glioma: Effects on Release of Extracellular Vesicles, Cell Viability, and Tumor Progression
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DOI: 10.3389/fmolb.2020.554649
Abstract: Introduction: Glioma cells exert influence over the tumor-microenvironment in part through the release of extracellular vesicles (EVs), membrane-enclosed structures containing proteins, lipids, and RNAs. In this study, we evaluated the function of Ras-associated protein 27a… read more here.
Keywords: tumor; glioma; rab27a; viability ... See more keywords
Rab3A/Rab27A System Silencing Ameliorates High Glucose-Induced Injury in Podocytes
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DOI: 10.3390/biology12050690
Abstract: Simple Summary In diabetic nephropathy, the injury of renal cells such as podocytes worsens the glomerular filtration process due to the cells’ loss and detachment from the basal membrane. Intra- and intercellular communications in cells… read more here.
Keywords: rab27a; rab3a rab27a; injury; rab27a system ... See more keywords