Coronin1C Is a GDP-Specific Rab44 Effector That Controls Osteoclast Formation by Regulating Cell Motility in Macrophages
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DOI: 10.3390/ijms23126619
Abstract: Osteoclasts are multinucleated bone-resorbing cells that are formed by the fusion of macrophages. Recently, we identified Rab44, a large Rab GTPase, as an upregulated gene during osteoclast differentiation that negatively regulates osteoclast differentiation. However, the… read more here.
Keywords: cell; rab44; osteoclast differentiation; coronin1c knockdown ... See more keywords
Rab44 Deficiency Induces Impaired Immune Responses to Nickel Allergy
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24020994
Abstract: Rab44 was recently identified as an atypical Rab GTPase that possesses EF-hand and coiled-coil domains at the N-terminus, and a Rab-GTPase domain at the C-terminus. Rab44 is highly expressed in immune-related cells such as mast… read more here.
Keywords: rab44; rab44 deficiency; rab44 deficient; deficient mice ... See more keywords