Extracellular adenosine‐induced Rac1 activation in pulmonary endothelium: Molecular mechanisms and barrier‐protective role
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26281
Abstract: We have previously shown that Gs‐coupled adenosine receptors (A2a) are primarily involved in adenosine‐induced human pulmonary artery endothelial cell (HPAEC) barrier enhancement. However, the downstream events that mediate the strengthening of the endothelial cell (EC)… read more here.
Keywords: rac1 activation; induced rac1; adenosine; adenosine induced ... See more keywords
Voltage‐dependent activation of Rac1 by Nav1.5 channels promotes cell migration
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29290
Abstract: Ion channels can regulate the plasma membrane potential (Vm) and cell migration as a result of altered ion flux. However, the mechanism by which Vm regulates motility remains unclear. Here, we show that the Nav1.5… read more here.
Keywords: rac1 activation; cell migration; migration; voltage dependent ... See more keywords
Time of Day-Dependent Alteration of Hippocampal Rac1 Activation Regulates Contextual Fear Memory in Rats
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.871679
Abstract: Fear memory in species varies according to the time of the day. Although the underlying molecular mechanisms have been extensively explored, they remain largely unknown. Here, we report that hippocampal Rac1 activity undergoes a time… read more here.
Keywords: fear memory; rac1 activation; rac1; hippocampal rac1 ... See more keywords