The Small GTPase Rac1 Increases Cell Surface Stiffness and Enhances 3D Migration Into Extracellular Matrices
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DOI: 10.1038/s41598-019-43975-0
Abstract: Membrane ruffling and lamellipodia formation promote the motility of adherent cells in two-dimensional motility assays by mechano-sensing of the microenvironment and initiation of focal adhesions towards their surroundings. Lamellipodium formation is stimulated by small Rho… read more here.
Keywords: rac1 knockout; motility; deformability; rac1 ... See more keywords