An Aminocaprolactam Racemase from Ochrobactrum anthropi with Promiscuous Amino Acid Ester Racemase Activity
Sign Up to like & getrecommendations! Published in 2018 at "ChemBioChem"
DOI: 10.1002/cbic.201800265
Abstract: The kinetic resolution of amino acid esters (AAEs) is a useful synthetic strategy for the preparation of single‐enantiomer amino acids. The development of an enzymatic dynamic kinetic resolution (DKR) process for AAEs, which would give… read more here.
Keywords: ester racemase; acid ester; amino; amino acid ... See more keywords
The first identification and characterization of a histidine-specific amino acid racemase, histidine racemase from a lactic acid bacterium, Leuconostoc mesenteroides subsp. sake NBRC 102480
Sign Up to like & getrecommendations! Published in 2018 at "Amino Acids"
DOI: 10.1007/s00726-018-2671-y
Abstract: We expressed a histidine racemase from Leuconostoc mesenteroides subsp. sake NBRC 102480 (Lm-HisR) successively in a soluble fraction of Escherichia coli BL21 (DE3) and then highly purified it from the cell-free extract. Lm-HisR showed amino… read more here.
Keywords: amino acid; histidine; hisr; acid racemase ... See more keywords
Commentary on "Urinary L-erythro-β-hydroxyasparagine - a novel serine racemase inhibitor and substrate of the Zn2+-dependent D-serine dehydratase".
Sign Up to like & getrecommendations! Published in 2021 at "Bioscience reports"
DOI: 10.1042/bsr20211524
Abstract: The analysis of the urine contents can be informative of physiological homeostasis, and it has been speculated that the levels of urinary D-serine (D-ser) could inform about neurological and renal disorders. By analysing the levels… read more here.
Keywords: commentary urinary; dehydratase; ser; racemase ... See more keywords
Identification of a new alanine racemase in Salmonella Enteritidis and its contribution to pathogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Gut Pathogens"
DOI: 10.1186/s13099-018-0257-6
Abstract: BackgroundNon-typhoidal Salmonella (NTS) infections caused primarily by S. Enteritidis and S. Typhimurium particularly in immunocompromised hosts have accounted for a large percentage of fatalities in developed nations. Antibiotics have revolutionized the cure of enteric infections… read more here.
Keywords: salmonella; vivo; alanine racemase; contribution ... See more keywords
Computational Molecular Modeling Studies of Some Mycobacterium Tuberculosis Alanine Racemase Inhibitors.
Sign Up to like & getrecommendations! Published in 2022 at "Acta chimica Slovenica"
DOI: 10.17344/acsi.2021.7267
Abstract: Alanine racemase is a pyridoxal-5'-phosphate dependent bacterial enzyme that provides the essential peptidoglycan precursor D-alanine, utilized for cell wall synthesis. This enzyme is ubiquitous throughout bacteria, including Mycobacterium tuberculosis, making it an attractive target for… read more here.
Keywords: racemase; mycobacterium tuberculosis; tuberculosis alanine; alanine racemase ... See more keywords
The Energy Landscape of Human Serine Racemase
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2018.00112
Abstract: Human serine racemase is a pyridoxal 5′-phosphate (PLP)-dependent dimeric enzyme that catalyzes the reversible racemization of L-serine and D-serine and their dehydration to pyruvate and ammonia. As D-serine is the co-agonist of the N-methyl-D-aspartate receptors… read more here.
Keywords: human serine; energy landscape; serine racemase; racemase ... See more keywords