Chemoenzymatic enantioselective and stereo-convergent syntheses of lisofylline enantiomers via lipase-catalyzed kinetic resolution and optical inversion approach
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DOI: 10.1016/j.mcat.2021.111451
Abstract: Abstract Highly enantioselective enzymatic kinetic resolution (EKR) of racemic lisofylline is presented for the first time. A comprehensive optimization of the key parameters of lipase-catalyzed transesterification of racemic lisofylline revealed that optimal biocatalytic system consisted… read more here.
Keywords: resolution; kinetic resolution; catalyzed kinetic; racemic lisofylline ... See more keywords