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   Articles with "racgap1" as a keyword



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Up-Regulation of RACGAP1 Promotes Progressions of Hepatocellular Carcinoma Regulated by GABPA via PI3K/AKT Pathway

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recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/3034150

Abstract: Hepatocellular carcinoma (HCC) is one of the dominating tumors causing death due to lack of timely discovery and valid treatment. Abnormal increase of Rac GTPase activating protein 1 (RACGAP1) has been verified to be an… read more here.

Keywords: pi3k akt; hepatocellular carcinoma; racgap1; hcc ... See more keywords
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Overexpression of RACGAP1 by E2F1 Promotes Neuroendocrine Differentiation of Prostate Cancer by Stabilizing EZH2 Expression.

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recommendations! Published in 2023 at "Aging and disease"

DOI: 10.14336/ad.2023.0202

Abstract: Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer. It is characterized by the loss of androgen receptor (AR) signaling in neuroendocrine transdifferentiation, and finally, resistance to AR-targeted therapy. With the application of… read more here.

Keywords: racgap1; prostate; prostate cancer; ezh2 expression ... See more keywords
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Effects of Shenkang Pills on Early-Stage Diabetic Nephropathy in db/db Mice via Inhibiting AURKB/RacGAP1/RhoA Signaling Pathway

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recommendations! Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.781806

Abstract: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease, so there is an urgent need to suppress its development at early stage. Shenkang pills (SKP) are a hospital prescription selected and optimized from… read more here.

Keywords: early stage; pharmacology; racgap1; stage ... See more keywords
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Rac GTPase activating protein 1 promotes gallbladder cancer via binding DNA ligase 3 to reduce apoptosis

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recommendations! Published in 2021 at "International Journal of Biological Sciences"

DOI: 10.7150/ijbs.58857

Abstract: Rac GTPase activating protein 1 (RACGAP1) has been characterized in the pathogenesis and progression of several malignancies, however, little is known regarding its role in the development of gallbladder cancer (GBC). This investigation seeks to… read more here.

Keywords: racgap1; apoptosis; gtpase activating; rac gtpase ... See more keywords