Integrin beta and receptor for activated protein kinase C are involved in the cell entry of Bombyx mori cypovirus
Sign Up to like & getrecommendations! Published in 2017 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-017-8158-z
Abstract: Receptor-mediated endocytosis using a β1 integrin-dependent internalization was considered as the primary mechanism for the initiation of mammalian reovirus infection. Bombyx mori cypovirus (BmCPV) is a member of Reoviridae family which mainly infects the midgut… read more here.
Keywords: rack1; cell entry; bmcpv; receptor ... See more keywords
Downregulation of tumor suppressor RACK1 by Helicobacter pylori infection promotes gastric carcinogenesis through the integrin β-1/NF-κB signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2019.02.039
Abstract: Receptor of activated protein kinase C 1 (RACK1) is downregulated in gastric cancer and is involved in modulating NF-κB signaling pathway activity. However, the underlying molecular mechanisms regulating RACK1 expression are unclear. In this study,… read more here.
Keywords: rack1; signaling pathway; pylori infection; expression ... See more keywords
The receptor for activated C kinase 1 (RACK1) mediating immune response in thick shell mussel Mytilus coruscus
Sign Up to like & getrecommendations! Published in 2018 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2018.04.004
Abstract: ABSTRACT The receptor for activated C kinase 1 (RACK1) is a intracellular receptor for the protein kinase C family which mediates various biological processes. Here, a novel RACK1 gene termed Mc‐RACK1 was identified from thick… read more here.
Keywords: activated kinase; mytilus coruscus; receptor activated; rack1 ... See more keywords
Overexpression of RACK1 enhanced the replication of porcine reproductive and respiratory syndrome virus in Marc-145 cells and promoted the NF-κB activation via upregulating the expression and phosphorylation of TRAF2.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.05.046
Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative pathogen for porcine reproductive and respiratory syndrome (PRRS), which lead to huge loss to porcine industry. RACK1 (receptor of activated protein C kinase 1) was… read more here.
Keywords: rack1; 145 cells; porcine reproductive; activation ... See more keywords
Role of RACK1 on cell proliferation, adhesion, and bortezomib-induced apoptosis in multiple myeloma.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.10.034
Abstract: Receptor for activated C kinase 1 (RACK1), a scaffold protein, plays a crucial role in the progression of various cancers. However, the biological function and underlying mechanism of RACK1 in multiple myeloma (MM) cells remain… read more here.
Keywords: myeloma; rack1; apoptosis; adhesion ... See more keywords
RACK1 is an organ-specific prognostic predictor in OSCC.
Sign Up to like & getrecommendations! Published in 2018 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2017.10.025
Abstract: OBJECTIVES This study aims to verify that RACK1 is an organ-specific prognostic predictor in patients with oral squamous cell carcinoma (OSCC). EXPERIMENTAL DESIGN The RACK1 expression level was assessed by immunohistochemistry (IHC) in a total… read more here.
Keywords: specific prognostic; organ specific; rack1; predictor ... See more keywords
Arabidopsis thaliana and Oryza sativa receptor for activated C kinase 1 (RACK1) mediated signaling pathway shows hypersensitivity to oxidative stress
Sign Up to like & getrecommendations! Published in 2021 at "Plant Gene"
DOI: 10.1016/j.plgene.2021.100299
Abstract: Abstract Scaffold proteins regulate cellular mechanisms and phenotypic patterns through protein-to-protein interactions. Receptor for Activated C Kinase 1 (RACK1) is a highly conserved protein containing 40 amino acid repeats of tryptophan-aspartic acid dipeptides (WD-repeat). RACK1… read more here.
Keywords: rack1; stress; thaliana; receptor activated ... See more keywords
The scaffold protein RACK1 is a target of endocrine disrupting chemicals (EDCs) with important implication in immunity
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2017.04.011
Abstract: ABSTRACT We recently demonstrated the existence of a complex hormonal balance between steroid hormones in the control of RACK1 (Receptor for Activated C Kinase 1) expression and immune activation, suggesting that this scaffold protein may… read more here.
Keywords: endocrine disrupting; rack1; target; scaffold protein ... See more keywords
RACK1 Regulates Poxvirus Protein Synthesis Independently of Its Role in Ribosome-Based Stress Signaling
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DOI: 10.1128/jvi.01093-22
Abstract: Receptor for activated C kinase 1 (RACK1) is a multifunctional ribosomal protein that regulates translation directly and mediates signaling to and from the ribosome. While recent work has shown that RACK1 is phosphorylated by vaccinia… read more here.
Keywords: stress; synthesis; stress signaling; rack1 ... See more keywords
RACK1 Associates with RNA-Binding Proteins Vigilin and SERBP1 to Facilitate Dengue Virus Replication
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01962-21
Abstract: We recently identified the scaffolding RACK1 protein as an important host-dependency factor for dengue virus (DENV), a positive-stranded RNA virus responsible for the most prevalent mosquito-borne viral disease worldwide. Here, we have performed the first… read more here.
Keywords: vigilin serbp1; replication; rack1; virus ... See more keywords
Abstract 1112: CCDC102B promotes metastatic cascade in breast cancer by activating NF-κB via down-regulating RACK1
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs18-1112
Abstract: Background: Breast cancer is one of the leading causes of cancer death among women and the pathological status of axillary lymph nodes is an important predictor of prognosis. However, the mechanism involved in this early… read more here.
Keywords: expression; ccdc102b; rack1; cancer ... See more keywords