Treatment of Uterine Sarcoma with rAd-p53 (Gendicine) Followed by Chemotherapy: Clinical Study of TP53 Gene Therapy
Sign Up to like & getrecommendations! Published in 2017 at "Human Gene Therapy"
DOI: 10.1089/hum.2017.206
Abstract: This study evaluated the efficacy of rAd-p53 (Gendicine®) followed by chemotherapy for the treatment of uterine sarcoma. Twelve cases of uterine sarcoma treated at Shengjing Hospital were retrospectively analyzed. Among the 12 patients, one had… read more here.
Keywords: followed chemotherapy; uterine sarcoma; rad; treatment ... See more keywords
Recombinant human p53 adenovirus injection (rAd-p53) combined with chemotherapy for 4 cases of high-grade serous ovarian cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Current gene therapy"
DOI: 10.2174/1566523220666200826100245
Abstract: High-grade serous ovarian carcinoma (HGSOC) is one of the most common ovarian epithelial carcinomas. It is highly invasive, easily recurs after systemic treatment, and has a poor prognosis. Despite many new chemotherapeutic drugs and trials… read more here.
Keywords: treatment; injection; p53; rad p53 ... See more keywords
The effects of interleukin 2 and rAd-p53 as a treatment for glioblastoma.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular medicine reports"
DOI: 10.3892/mmr.2018.8408
Abstract: Interleukin 2 (IL-2) is an anti-cancer cytokine that stimulates T cell propagation, triggering innate and adaptive immunity. IL-2 has been used for cancer therapy and has achieved curative effects. Recombinant adenovirus p53 injection (rAd‑p53) is… read more here.
Keywords: p53; rad p53; p53 treatment; tumor ... See more keywords
p53-dependent apoptosis is essential for the antitumor effect of paclitaxel response to DNA damage in papillary thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Medical Sciences"
DOI: 10.7150/ijms.61944
Abstract: A functional p53 protein plays an important role in killing tumor cells. Previous studies showed that chemotherapeutic drug, paclitaxel (PTX), showed anti-tumor activity through inducing G2/M arrest and apoptosis by targeting microtubules in tumor cells.… read more here.
Keywords: ptc cells; apoptosis; ptx; p53 ... See more keywords