Diverse roles of RAD18 and Y-family DNA polymerases in tumorigenesis
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DOI: 10.1080/15384101.2018.1456296
Abstract: ABSTRACT Mutagenesis is a hallmark and enabling characteristic of cancer cells. The E3 ubiquitin ligase RAD18 and its downstream effectors, the ‘Y-family’ Trans-Lesion Synthesis (TLS) DNA polymerases, confer DNA damage tolerance at the expense of… read more here.
Keywords: family dna; dna; rad18 family; dna polymerases ... See more keywords