SNAI1-Driven Sequential EMT Changes Attributed by Selective Chromatin Enrichment of RAD21 and GRHL2
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DOI: 10.3390/cancers12051140
Abstract: Over two decades of research on cancer-associated epithelial-mesenchymal transition (EMT) led us to ascertain the occurrence of transitional intermediate states (collectively referred to as the EMT spectrum). Among the molecular factors that drive EMT, SNAI1… read more here.
Keywords: emt changes; emt; sequential emt; rad21 ... See more keywords
Recurrent Germline Variant in RAD21 Predisposes Children to Lymphoblastic Leukemia or Lymphoma
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DOI: 10.3390/ijms23095174
Abstract: Somatic loss of function mutations in cohesin genes are frequently associated with various cancer types, while cohesin disruption in the germline causes cohesinopathies such as Cornelia-de-Lange syndrome (CdLS). Here, we present the discovery of a… read more here.
Keywords: rad21; leukemia lymphoma; lymphoblastic leukemia; germline ... See more keywords
Prognostic Values and Underlying Regulatory Network of Cohesin Subunits in Esophageal Carcinoma
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DOI: 10.7150/jca.66949
Abstract: Background: Cohesin is a highly conserved and ubiquitously expressed protein complex. While increasing evidence suggests that cohesin dysregulation is vital in the carcinogenesis of numerous malignancies, little is known about the prognostic values and potential… read more here.
Keywords: rad21; expression; analysis; stag2 rad21 ... See more keywords