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   Articles with "rad21" as a keyword



Mechanism of METTL14-mediated RAD21 mRNA epigenetic transcriptome modification in inhibiting thyroid cancer development

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recommendations! Published in 2025 at "World Journal of Surgical Oncology"

DOI: 10.1186/s12957-025-04024-5

Abstract: This study investigated the mechanism of methyltransferase-like 14 (METTL14)-mediated epigenetic transcriptome modification of RAD21 mRNA in inhibiting thyroid cancer (TC) development. TCGA and Starbase databases were used to predict the differential expression of METTL14 in… read more here.

Keywords: rad21 mrna; mettl14; mettl14 mediated; cell ... See more keywords
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SNAI1-Driven Sequential EMT Changes Attributed by Selective Chromatin Enrichment of RAD21 and GRHL2

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recommendations! Published in 2020 at "Cancers"

DOI: 10.3390/cancers12051140

Abstract: Over two decades of research on cancer-associated epithelial-mesenchymal transition (EMT) led us to ascertain the occurrence of transitional intermediate states (collectively referred to as the EMT spectrum). Among the molecular factors that drive EMT, SNAI1… read more here.

Keywords: emt changes; emt; sequential emt; rad21 ... See more keywords

Recurrent Germline Variant in RAD21 Predisposes Children to Lymphoblastic Leukemia or Lymphoma

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23095174

Abstract: Somatic loss of function mutations in cohesin genes are frequently associated with various cancer types, while cohesin disruption in the germline causes cohesinopathies such as Cornelia-de-Lange syndrome (CdLS). Here, we present the discovery of a… read more here.

Keywords: rad21; leukemia lymphoma; lymphoblastic leukemia; germline ... See more keywords

Prognostic Values and Underlying Regulatory Network of Cohesin Subunits in Esophageal Carcinoma

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recommendations! Published in 2022 at "Journal of Cancer"

DOI: 10.7150/jca.66949

Abstract: Background: Cohesin is a highly conserved and ubiquitously expressed protein complex. While increasing evidence suggests that cohesin dysregulation is vital in the carcinogenesis of numerous malignancies, little is known about the prognostic values and potential… read more here.

Keywords: rad21; expression; analysis; stag2 rad21 ... See more keywords