Identification of cancer biomarkers of prognostic value using specific gene regulatory networks (GRN): a novel role of RAD51AP1 for ovarian and lung cancers
Sign Up to like & getrecommendations! Published in 2018 at "Carcinogenesis"
DOI: 10.1093/carcin/bgx122
Abstract: We provide evidence of how RAD51AP1 can be of importance as potential biomarker since it is overexpressed in both tissue and peripheral blood of ovarian and lung cancer patients. Silencing of the gene can also… read more here.
Keywords: identification cancer; gene; ovarian lung; rad51ap1 ... See more keywords
RAD51AP1 Deficiency Reduces Tumor Growth by Targeting Stem Cell Self-Renewal
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/0008-5472.can-19-3713
Abstract: This study provides in vivo evidence that RAD51AP1 plays a critical role in breast cancer growth and metastasis by regulating breast cancer stem cell self-renewal. RAD51-associated protein 1 (RAD51AP1) plays an integral role in homologous… read more here.
Keywords: growth; self renewal; cancer; breast cancer ... See more keywords
RAD51AP1 and RAD54L Can Underpin Two Distinct RAD51-Dependent Routes of DNA Damage Repair via Homologous Recombination
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.866601
Abstract: Homologous recombination DNA repair (HR) is a complex DNA damage repair pathway and an attractive target of inhibition in anti-cancer therapy. To help guide the development of efficient HR inhibitors, it is critical to identify… read more here.
Keywords: dna damage; rad51ap1 rad54l; rad51ap1; homologous recombination ... See more keywords