A decade of RAD51C and RAD51D germline variants in cancer
Sign Up to like & getrecommendations! Published in 2021 at "Human Mutation"
DOI: 10.1002/humu.24319
Abstract: Defects in DNA repair genes have been extensively associated with cancer susceptibility. Germline pathogenic variants (GPV) in genes involved in homologous recombination repair pathways predispose to cancers arising mainly in the breast and ovary, but… read more here.
Keywords: cancer; germline variants; rad51d germline; variants cancer ... See more keywords
Contribution of RAD51D germline mutations in breast and ovarian cancer in Greece
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Human Genetics"
DOI: 10.1038/s10038-018-0498-8
Abstract: RAD51D gene’s protein product is known to be involved in the DNA repair mechanism by homologous recombination. RAD51D germline mutations have been recently associated with ovarian and breast cancer (OC and BC, respectively) predisposition. Our… read more here.
Keywords: cancer; rad51d germline; contribution rad51d; germline mutations ... See more keywords