Articles with "rad52 brca2" as a keyword



Photo from wikipedia

POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis.

Sign Up to like & get
recommendations!
Published in 2021 at "Nature cell biology"

DOI: 10.1038/s41556-021-00764-0

Abstract: BRCA2-mutant cells are defective in homologous recombination, making them vulnerable to the inactivation of other pathways for the repair of DNA double-strand breaks (DSBs). This concept can be clinically exploited but is currently limited due… read more here.

Keywords: end joining; mitosis; mediated end; brca2 ... See more keywords