The cryo‐EM structure of full‐length RAD52 protein contains an undecameric ring
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DOI: 10.1002/2211-5463.13565
Abstract: The human RAD52 protein, which forms an oligomeric ring structure, is involved in DNA double‐strand break repair. The N‐terminal half of RAD52 is primarily responsible for self‐oligomerisation and DNA binding. Crystallographic studies have revealed the… read more here.
Keywords: terminal half; rad52 protein; structure; cryo ... See more keywords
DSS1 interacts with and stimulates RAD52 to promote the repair of DSBs
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DOI: 10.1093/nar/gkz1052
Abstract: Abstract The proper repair of deleterious DNA lesions such as double strand breaks prevents genomic instability and carcinogenesis. In yeast, the Rad52 protein mediates DSB repair via homologous recombination. In mammalian cells, despite the presence… read more here.
Keywords: rad52 protein; dss1; repair dsbs; repair ... See more keywords